BDBM451799 2-amino-N-((1r,4R)-4-hydroxycyclohexyl)-5-(4-(((R)-2-methylpyrrolidin-1-yl)methyl)phenyl)nicotinamide::US10710980, Example 31::US10947218, Example 31

SMILES C[C@@H]1CCCN1Cc1ccc(cc1)-c1cnc(N)c(c1)C(=O)N[C@H]1CC[C@H](O)CC1

InChI Key InChIKey=WTEJOBNHOMFLQN-MAODMQOUSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 451799   

TargetBone morphogenetic protein receptor type-1B(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451799(2-amino-N-((1r,4R)-4-hydroxycyclohexyl)-5-(4-(((R)...)
Affinity DataIC50:  4.50E+3nMAssay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for wild-type ALK2 (aa172-499), ALK2 FOP mutant (aa172-499 R20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBone morphogenetic protein receptor type-1B(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451799(2-amino-N-((1r,4R)-4-hydroxycyclohexyl)-5-(4-(((R)...)
Affinity DataIC50:  4.50E+3nMAssay Description:In the applied method, this separation takes place inside a chip that contains a complex capillary system for simultaneous analysis of 12 samples (“1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent